NeuropeptidesPreclinical
The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system
Benoist CC, Wright JW, Zhu M, et al. · J Pharmacol Exp Ther · 2014
PMID: 25187433 · DOI: 10.1124/jpet.114.216648
Summary
Mechanistic in vitro and rat in vivo study characterizing dihexa and Nle1-AngIV effects via HGF/c-Met. Endpoints: c-Met phosphorylation, hippocampal spinogenesis, Morris water-maze performance.
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Compounds referenced in this study
- View product →DihexaAngiotensin IV analog studied in synaptogenesis and HGF/c-Met receptor research.
Guides covering this compound
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