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GLP-1 family

Tirzepatide Once Weekly for the Treatment of Obesity

Jastreboff AM, Aronne LJ, Ahmad NN, et al. · N Engl J Med · 2022
PMID: 35658024 · DOI: 10.1056/NEJMoa2206038
Summary

Phase 3 randomized, double-blind, placebo-controlled trial (SURMOUNT-1) of once-weekly tirzepatide 5/10/15 mg vs placebo over 72 weeks in 2539 adults with obesity without diabetes. Primary endpoint: percent change in body weight.

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Compounds referenced in this study
  • GLP-2 T
    Dual-receptor incretin class agonist studied in metabolic-pathway research.
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