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GLP-1 family

A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management

Pi-Sunyer X, Astrup A, Fujioka K, et al. · N Engl J Med · 2015
PMID: 26132939 · DOI: 10.1056/NEJMoa1411892
Summary

56-week double-blind randomized trial (SCALE) in 3731 adults without type 2 diabetes; once-daily subcutaneous liraglutide 3.0 mg vs placebo, both with lifestyle counseling. Primary endpoint: change in body weight.

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Compounds referenced in this study
  • GLP-1 S
    Single-receptor incretin class agonist studied in incretin-pathway metabolic research.
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