Neuropeptides

The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases

Wright JW, Harding JW. · Prog Neurobiol · 2015

PMID: 25455861 · DOI: 10.1016/j.pneurobio.2014.10.002

Summary

Review consolidating angiotensin IV analog development including dihexa, BBB permeability, and HGF/c-Met-mediated synaptogenesis findings across rodent learning and memory paradigms.

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Compounds referenced in this study

Dihexa
Angiotensin IV analog studied in synaptogenesis and HGF/c-Met receptor research.
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Guides covering this compound

Dihexa — why it is not really a peptide
Dihexa is an angiotensin IV analog built with non-amino-acid components. Peptide COA conventions apply to it only partly, and that trips people up.
2 min read

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