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Immune

The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium

Heilborn JD, Nilsson MF, Kratz G, et al. · J Invest Dermatol · 2003
PMID: 12603850 · DOI: 10.1046/j.1523-1747.2003.12120.x
Summary

Human acute vs chronic skin-wound study characterizing LL-37 expression in re-epithelializing epidermis. Endpoints: immunohistochemistry, in vitro keratinocyte migration with LL-37 blockade.

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Compounds referenced in this study
  • LL-37
    37-residue human cathelicidin antimicrobial peptide studied in innate-immunity and wound-healing research.
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