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Immune

The efficacy and safety of thymosin alpha-1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial

Liu D, Yu Z, Yin J, et al. · BMJ · 2025
PMID: 39814420 · DOI: 10.1136/bmj-2024-082583
Summary

Multicenter double-blind placebo-controlled phase 3 trial (TESTS) of subcutaneous thymosin alpha-1 in 1106 adults with sepsis. Primary endpoint: 28-day all-cause mortality; secondary: organ-failure-free days.

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Compounds referenced in this study
  • Thymosin Alpha-1 5mg
    28-residue acetylated thymic peptide studied in immune-modulation research.
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