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Tesamorelin

Stabilized GHRH analog studied in lipodystrophy and visceral-adiposity research models.

Tesamorelin is a synthetic analog of growth-hormone-releasing hormone (GHRH) — the full 44-amino-acid native sequence stabilized with a trans-hexenoic acid modification that protects it from rapid enzymatic cleavage. It acts on the pituitary GHRH receptor, driving pulsatile growth-hormone release that preserves the natural feedback architecture of the axis.

It carries one of the deeper research records in the GHRH family, including substantial human clinical literature around body-composition endpoints — which distinguishes it from most compounds in this catalog and makes it a frequent reference standard in GH-axis study designs.

Tesamorelin is often studied alongside ghrelin-receptor secretagogues like ipamorelin, since the two engage complementary receptors on the same axis. Supplied lyophilized, HPLC-verified per lot, for laboratory research.

Research use only. Everything on this page describes laboratory research. This compound is supplied strictly for in-vitro research use; it is not approved by the FDA for human or veterinary use, and nothing here is a protocol or a recommendation.

Published research

  • Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension
    Falutz J, et al. J Acquir Immune Defic Syndr. 2010.PubMed
  • Metabolic Effects of a Growth Hormone-Releasing Factor in Patients with HIV
    Falutz J, et al. N Engl J Med. 2007.PubMed

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