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GH secretagogues

Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog

Ionescu M, Frohman LA. · J Clin Endocrinol Metab · 2006
PMID: 17018654 · DOI: 10.1210/jc.2006-1328
Summary

Healthy-adult pharmacodynamic study characterizing pulsatile GH secretion under sustained CJC-1295 stimulation via frequent sampling. Endpoints: GH pulse frequency/amplitude, IGF-I trajectory.

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Compounds referenced in this study
  • CJC-1295 with DAC 5mg
    GHRH analog with drug-affinity complex. Extended-half-life GH-axis research peptide.
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  • CJC-1295 (no DAC)
    Modified GHRH (1-29) analog without drug-affinity complex. Short half-life GH-axis research peptide.
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