
ECM / tissue-repair research
TB-500 (Long Chain)
CAS 77591-33-4
Molecular data
- CAS number
- 77591-33-4
- Mol. formula
- C212H350N56O78S
- Mol. weight
- 4963.44 g/mol
- Sequence
- N-Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
- Purity
- ≥ 99.0%
- Lot number
- Assigned at shipment
Certificate of Analysis
Independent third-party verified
Summary
CAS 77591-33-4 · 4963.44 g/mol · ≥99% by HPLC · from $38 (single) to $66 (10-pack)
Synthetic acetylated thymosin-β4 (1-43) analog. Studied in tissue-regeneration research.
Read the full TB-500 (Long Chain) compound profile — mechanism, published research, and references →
Research context
Goldstein et al., Ann NY Acad Sci (2012).
More in Tissue Repair & Remodeling
Bundled in these stacks
Handling & reference
- TB-500 and thymosin beta-4 — what you are actually buyingTB-500 and thymosin beta-4 are used interchangeably by suppliers but originally named different molecules. How to tell from the COA which one is in the vial.
- Choosing a US peptide supplier for a clinic or storeWhat separates suppliers when everyone's website says the same thing: where the material is made, who tests it, and what they will put in writing.
- Peptide purity thresholds — 95%, 98%, 99% and what each is good forWhat HPLC area-percent purity levels actually mean for downstream applications, why "higher is better" is not always true, and the cost trade-offs.
- A Certificate of Analysis in your name — what it coversA re-issued COA changes whose letterhead the data appears on. It does not change the data, the lot, or who performed the analysis — and claiming otherwise is where operators get into trouble.
Published research
Primary literature on this compound — trial design, endpoints and limitations. Summaries, not recommendations.
- Thymosin beta 4 improves dermal burn wound healing via downregulation of receptor of advanced glycation end products in db/db miceBiochim Biophys Acta · 2014 · animal study
- Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged miceWound Repair Regen · 2003 · animal study
- Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injuryExp Eye Res · 2002 · animal study
- Thymosin beta4 accelerates wound healingJ Invest Dermatol · 1999 · animal study
About TB-500 (Long Chain)
- What is TB-500 (Long Chain)?
- Synthetic acetylated thymosin-β4 (1-43) analog. Studied in tissue-regeneration research.
- What is the CAS number for TB-500 (Long Chain)?
- TB-500 (Long Chain) is registered under CAS Registry Number 77591-33-4.
- What is the molecular formula of TB-500 (Long Chain)?
- The molecular formula of TB-500 (Long Chain) is C212H350N56O78S, with a molecular weight of 4963.44 g/mol.
- What research context is TB-500 (Long Chain) studied in?
- Goldstein et al., Ann NY Acad Sci (2012).
- What's included with each TB-500 (Long Chain) lot?
- Every lot of TB-500 (Long Chain) ships with a per-lot Certificate of Analysis (COA) from an independent US laboratory documenting ≥99.0% purity by HPLC and mass-spectrometry identity confirmation. The COA is QR-linked from the vial label.
- How is TB-500 (Long Chain) verified?
- Each lot of TB-500 (Long Chain) is independently verified at Chromate.org, a US analytical laboratory, with HPLC purity, mass-spectrometry identity, and heavy-metal screening. The per-lot Certificate of Analysis is published on this page and ships printed in every package.
- How is TB-500 (Long Chain) stored?
- Lyophilized TB-500 (Long Chain) is shipped at ambient temperature in protective packaging. For long-term laboratory storage, refer to the per-lot Certificate of Analysis storage notes specific to the lot you receive.
- Is TB-500 (Long Chain) approved for human or veterinary use?
- No. This product is for laboratory research use only. Not for human or veterinary use. Not a drug, supplement, or medical device. Customers certify research use at checkout per our Terms of Sale.
Research use only
This product is for laboratory research use only. Not for human or veterinary use. Not a drug, supplement, or medical device. By purchasing, customer certifies research use per our Terms of Sale.

