BPC-157
15-amino-acid synthetic pentadecapeptide derived from body-protection compound. Tissue-repair research peptide.
BPC-157 is a synthetic pentadecapeptide — fifteen amino acids — derived from a partial sequence of a protective protein first characterized in gastric juice. It is one of the most widely handled compounds in tissue-repair research, with a literature spanning tendon, ligament, muscle, and gastrointestinal injury models.
Most of what is known about BPC-157 comes from animal work: rodent models of tendon transection, muscle crush, and induced gastrointestinal damage, where investigators have reported effects on angiogenesis, fibroblast migration, and growth-factor expression. Human clinical evidence remains thin, which is exactly why the compound stays in the research column rather than the medicine cabinet.
In the lab it is prized for being robust: BPC-157 is stable in lyophilized form at room temperature for shipping, tolerates reconstitution well, and its short sequence makes identity verification by mass spectrometry unambiguous. Every Bench Grade lot ships with a Certificate of Analysis carrying the HPLC purity trace and verified molecular weight.
Published research
- BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone HealingSikiric P, et al. Curr Pharm Des. 2018.PubMed →
- The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migrationChang CH, et al. J Appl Physiol. 2011.PubMed →
- Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat
- Gastric pentadecapeptide BPC 157 as an effective therapy for muscle crush injury in the rat
- Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: promoted tendon-to-bone healing and opposed corticosteroid aggravation
- Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth