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Tissue repairPreclinical

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

Xiao B, Xu Z, Viennois E, et al. · Mol Ther · 2017
PMID: 28456380 · DOI: 10.1016/j.ymthe.2016.11.014
Summary

Murine DSS colitis model characterizing orally administered KPV-loaded hyaluronic acid nanoparticles. Endpoints: colonic targeting, inflammation markers, histologic damage scoring.

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Compounds referenced in this study
  • KPV
    C-terminal α-MSH tripeptide studied in inflammation and gut-mucosal research.
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Guides covering this compound
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