Tissue repairPreclinical
Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
Xiao B, Xu Z, Viennois E, et al. · Mol Ther · 2017
PMID: 28456380 · DOI: 10.1016/j.ymthe.2016.11.014
Summary
Murine DSS colitis model characterizing orally administered KPV-loaded hyaluronic acid nanoparticles. Endpoints: colonic targeting, inflammation markers, histologic damage scoring.
Citation hosted by NCBI. We link to the source so the researcher can read the abstract, full text, or references-cited list directly.
Compounds referenced in this study
- View product →KPVC-terminal α-MSH tripeptide studied in inflammation and gut-mucosal research.
Guides covering this compound
- Working out concentration and volume — the arithmeticConcentration, volume and mass are one equation rearranged three ways. The method, the unit traps, the peptide-content correction, and worked examples you can substitute your own figures into.5 min read
- Thymosin Alpha-1 — identity and the clinical literatureA 28-residue N-acetylated thymic peptide with more clinical literature behind it than almost any compound in this market. Identity data and what the studies covered.2 min read
- LL-37 (Cathelicidin) — identity and handling of a cationic peptide37 residues carrying an unusually high positive charge. That charge governs its solubility, its adsorption to surfaces, and why it needs different labware.2 min read
- Selank — a tuftsin analog, and the tail it shares with SemaxSelank is tuftsin with the same Pro-Gly-Pro tail Semax carries. Two compounds, one structural idea, and no methionine to worry about.2 min read
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