Tissue repairPreclinical
The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity
Kim SJ, Mehta HH, Wan J, et al. · Physiol Rep · 2019
PMID: 31293078 · DOI: 10.14814/phy2.14171
Summary
Mouse and human plasma study characterizing MOTS-c as a regulator of metabolites and insulin sensitivity. Endpoints: metabolomic profile, glucose disposal, exercise-associated MOTS-c levels.
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Compounds referenced in this study
- View product →MOTS-cMitochondrial-derived 16-residue peptide studied in metabolic-homeostasis and exercise-physiology research.
Guides covering this compound
- Epitalon — identity, chemistry and what the literature examinedA four-residue peptide at 390 g/mol, among the smallest compounds in the research market. CAS, formula, sequence, and what the published work actually studied.3 min read
- Semax — an ACTH fragment with a Pro-Gly-Pro tailSemax is ACTH (4-7) with a proline-glycine-proline tail attached. That tail is a design decision shared with Selank, and it explains both compounds.2 min read
- Dihexa — why it is not really a peptideDihexa is an angiotensin IV analog built with non-amino-acid components. Peptide COA conventions apply to it only partly, and that trips people up.2 min read
- Has my peptide gone bad? What you can and cannot tellSome degradation is visible and some is completely invisible. What appearance actually tells you about a vial, and where looking stops working.3 min read
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- The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin ResistanceCell Metab · 2015
