Senescence / mitochondrial research
MOTS-c
CAS 1627580-64-6
Molecular data
- CAS number
- 1627580-64-6
- Mol. formula
- C101H152N28O22S2
- Mol. weight
- 2174.61 g/mol
- Sequence
- Mitochondrial 12S rRNA-encoded 16-residue peptide
- Purity
- ≥ 99.0%
- Lot number
- Assigned at shipment
Certificate of Analysis
Independent third-party verified
- Purity (HPLC)
- 99.79%
- Batch
- 00011/0011
- Laboratory
- AV Analytics
- Analyzed
- Sep 3, 2026
Summary
CAS 1627580-64-6 · 2174.61 g/mol · ≥99% by HPLC · from $44 (single) to $78 (10-pack)
Mitochondrial-derived 16-residue peptide studied in metabolic-homeostasis and exercise-physiology research.
Read the full MOTS-c compound profile — mechanism, published research, and references →
Research context
Lee et al., Cell Metab (2015).
More in Longevity & Cellular
Bundled in these stacks
Handling & reference
- MOTS-c — a peptide encoded outside the nuclear genomeMOTS-c is encoded in mitochondrial 12S rRNA rather than nuclear DNA. What that means for identity checks, and the methionine that governs its handling.
- Dihexa — why it is not really a peptideDihexa is an angiotensin IV analog built with non-amino-acid components. Peptide COA conventions apply to it only partly, and that trips people up.
- Epitalon — identity, chemistry and what the literature examinedA four-residue peptide at 390 g/mol, among the smallest compounds in the research market. CAS, formula, sequence, and what the published work actually studied.
- HPLC vs mass spec vs amino acid analysis — what each test provesA practical guide to the three peptide QC methods, what each can prove and disprove, and why a complete QC profile requires all three.
Published research
Primary literature on this compound — trial design, endpoints and limitations. Summaries, not recommendations.
- The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivityPhysiol Rep · 2019 · animal study
- The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin ResistanceCell Metab · 2015 · animal study
- The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin ResistanceCell Metab · 2015 · animal study
About MOTS-c
- What is MOTS-c?
- Mitochondrial-derived 16-residue peptide studied in metabolic-homeostasis and exercise-physiology research.
- What is the CAS number for MOTS-c?
- MOTS-c is registered under CAS Registry Number 1627580-64-6.
- What is the molecular formula of MOTS-c?
- The molecular formula of MOTS-c is C101H152N28O22S2, with a molecular weight of 2174.61 g/mol.
- What research context is MOTS-c studied in?
- Lee et al., Cell Metab (2015).
- What's included with each MOTS-c lot?
- Every lot of MOTS-c ships with a per-lot Certificate of Analysis (COA) from an independent US laboratory documenting ≥99.0% purity by HPLC and mass-spectrometry identity confirmation. The COA is QR-linked from the vial label.
- How is MOTS-c verified?
- Each lot of MOTS-c is independently verified at Chromate.org, a US analytical laboratory, with HPLC purity, mass-spectrometry identity, and heavy-metal screening. The per-lot Certificate of Analysis is published on this page and ships printed in every package.
- How is MOTS-c stored?
- Lyophilized MOTS-c is shipped at ambient temperature in protective packaging. For long-term laboratory storage, refer to the per-lot Certificate of Analysis storage notes specific to the lot you receive.
- Is MOTS-c approved for human or veterinary use?
- No. This product is for laboratory research use only. Not for human or veterinary use. Not a drug, supplement, or medical device. Customers certify research use at checkout per our Terms of Sale.
Research use only
This product is for laboratory research use only. Not for human or veterinary use. Not a drug, supplement, or medical device. By purchasing, customer certifies research use per our Terms of Sale.