
MOTS-c
This product is for laboratory research use only. Not for human or veterinary use. Not a drug, supplement, or medical device.
MOTS-c is supplied by Bench Grade Peptides as a lyophilized powder in a sealed, lot-numbered vial, for laboratory research use only — not for human or veterinary use.
Its published Certificate of Analysis (lot 00011/0011, analyzed September 3, 2026) is from AV Analytics, a third-party laboratory, and reports 99.79% purity by HPLC; every published lot is listed on the product's COA page. Vials ship at ambient temperature in protective packaging from Florida (Bench Grade Peptides LLC is registered in Dover, Delaware), with storage notes on the lot's certificate.
Under the Bench Grade Guarantee, if an ISO 17025-accredited US laboratory of the buyer's choosing reports a result that disagrees with the published Certificate of Analysis, Bench Grade refunds the order and shipping to the original payment method and pays the lab fee plus $100 separately, by a payment method arranged with the buyer.
Certificate of analysis
Independent laboratory report.
- Report sample
- 10 mg
- Purity (HPLC)
- 99.79%
- Batch
- 00011/0011
- Laboratory
- AV Analytics
- Analyzed
- Sep 3, 2026
This certificate documents the sample and batch shown above. Match the report to your vial label; contact us if you need a different size or lot. All lots for this product.
Overview
Mitochondrial-derived 16-residue peptide studied in metabolic-homeostasis and exercise-physiology research.
Read the full MOTS-c compound profile — mechanism, published research, and references →
- Sequence
- Mitochondrial 12S rRNA-encoded 16-residue peptide
- Purity spec
- ≥ 99.0%
- Form
- Lyophilized powder
CAS 1627580-64-6 · 2174.61 g/mol · Purity specification: ≥99% by HPLC · $87.00–$133.00 depending on selected option
Molecular data
- CAS number
- 1627580-64-6
- Mol. formula
- C101H152N28O22S2
- Mol. weight
- 2174.61 g/mol
- Sequence
- Mitochondrial 12S rRNA-encoded 16-residue peptide
- Purity
- ≥ 99.0%
- Lot number
- Assigned at shipment
Research context
Lee et al., Cell Metab (2015).
Published research
Primary literature on this compound — trial design, endpoints and limitations. Summaries, not recommendations.
- The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivityPhysiol Rep · 2019 · animal study · PMID 31293078 · DOI 10.14814/phy2.14171
- The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin ResistanceCell Metab · 2015 · animal study · PMID 25738459 · DOI 10.1016/j.cmet.2015.02.009
- The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin ResistanceCell Metab · 2015 · animal study · PMID 25738459 · DOI 10.1016/j.cmet.2015.02.009
From the journal
Storage & handling
Lyophilized MOTS-c is shipped at ambient temperature in protective packaging. For long-term laboratory storage, keep vials sealed at –20°C, and where your lot's Certificate of Analysis is published, follow its storage notes.
Handling & reference
- MOTS-c — a peptide encoded outside the nuclear genomeMOTS-c is encoded in mitochondrial 12S rRNA rather than nuclear DNA. What that means for identity checks, and the methionine that governs its handling.
- Dihexa — why it is not really a peptideDihexa is an angiotensin IV analog built with non-amino-acid components. Peptide COA conventions apply to it only partly, and that trips people up.
- Epitalon — identity, chemistry and what the literature examinedA four-residue peptide at 390 g/mol, among the smallest compounds in the research market. CAS, formula, sequence, and what the published work actually studied.
- HPLC vs mass spec vs amino acid analysis — what each test provesA practical guide to the three peptide QC methods, what each can prove and disprove, and why a complete QC profile requires all three.
About MOTS-c
- What is MOTS-c?
- Mitochondrial-derived 16-residue peptide studied in metabolic-homeostasis and exercise-physiology research.
- What is the CAS number for MOTS-c?
- MOTS-c is registered under CAS Registry Number 1627580-64-6.
- What is the molecular formula of MOTS-c?
- The molecular formula of MOTS-c is C101H152N28O22S2, with a molecular weight of 2174.61 g/mol.
- Which laboratory issued the published certificate for MOTS-c?
- The published certificate from AV Analytics records the analysis for the product and batch named in that document. Refer to the report for the tests performed and results; it does not establish testing for every vial size or shipping lot.
Verified buyer reviews
★ 5.0 · 4 verified buyer reviews across the store
From customers we can match to a delivered order. We publish every review, good or bad, and remove only personal details and health or dosing statements (research material — we don't publish results claims). How reviews work
Showing 1 of 1 review.
- Steven G.Verified buyer
Quality
Shipping My vials were all securely packaged and arrived in great condition.
Customer experience Great communication, super fast shipping, items arrived well packaged. I will definitely be ordering again!
Before you order
- Independent report available. Lot 00011/0011 · 99.79% purity by HPLC · AV AnalyticsView the COA →
- UPS Ground ships free on 3 or more vials or on orders of $100 or more, UPS 2-Day at $250 or more and UPS Next Day Air at $600 or more (products after discounts; water does not count). Below those, UPS Ground is $20, UPS 2-Day $15 and UPS Next Day Air $60. Order by 2 PM ET on a business day and it ships the same day.Shipping →
- If a third-party lab disagrees with our COA, full refund plus $100.Guarantee →
- Pay by card.Payments →
- Made in the USA. Synthesized in an ISO-7 cleanroom. Match any laboratory report to the product and lot on your vial.Facility →
- Synthesized at a US facility in an ISO-7 certified cleanroom; filled and finished by a cGMP-certified US manufacturing partner.
- Secure facility with 24-hour CCTV cold-chain storage and time-locked chain-of-custody protocols.
- The published certificate from AV Analytics records the analysis for the product and batch named in that document. Refer to the report for the tests performed and results; it does not establish testing for every vial size or shipping lot.
- Open the published Certificate of Analysis below and match its product, vial size and batch to your vial. Contact us if you need help confirming the applicable report.
- US-domestic shipping only · Free UPS Ground on 3+ vials or $100+ · 2-Day $15, free at $250+.
More in Longevity & Cellular
Bundled in these stacks
Reselling, or buying at wholesale volume? See wholesale and white-label peptide supply.

